Tag: science (Page 1 of 2)

GRAY MATTERS by Theodore H. Schwartz

December 17, 2024 / aylah234@hotmail.com / 0 Comments

We’ve all heard the phrase “it’s not brain surgery.” But what exactly is brain surgery? It’s a profession that is barely a hundred years old and profoundly connects two human beings, but few know how it works, or its history. How did early neurosurgeons come to understand the human brain—an extraordinarily complex organ that controls everything we do, and yet at only three pounds is so fragile? And how did this incredibly challenging and lifesaving specialty emerge?

In this warm, rigorous, and deeply insightful book, Dr. Theodore H. Schwartz explores what it’s like to hold the scalpel, wield the drill, extract a tumor, fix a bullet hole, and remove a blood clot—when every second can mean life or death. Drawing from the author’s own cases, plus media, sports, and government archives, this seminal work delves into all the brain-related topics that have long-consumed public curiosity, like what really happened to JFK, President Biden’s brain surgery, and the NFL’s management of CTE. Dr. Schwartz also surveys the field’s latest incredible advances and discusses the philosophical questions of the unity of the self and the existence of free will.

A neurosurgeon as well as a professor of neurosurgery at Weill Cornell Medicine, one of the busiest and most highly ranked neurosurgery centers in the world, Dr. Schwartz tells this story like no one else could. Told through anecdote and clear explanation, this is the ultimate cultural and scientific history of a literally mind-blowing human endeavor, one that cuts to the core of who we are.

Thanks to NetGalley the author, and Dutton for this review copy!

GRAY MATTERS is a fascinating exploration of the brain’s potential, expertly balancing scientific insight with philosophical contemplation. As a practicing neurosurgeon, Schwartz has a unique vantage point into the wonders and mysteries of the human brain, which he translates into an engaging and accessible narrative. The book dives deep into the gray matter—the seat of human cognition, emotion, and identity—and asks profound questions about the nature of consciousness, technology’s impact on the brain, and the future of neuroscience.

One of the strengths of this book is its ability to make complex medical concepts accessible to a general audience. Schwartz explains the anatomy and physiology of the brain in clear and concise terms, making it easy for readers to follow along. He also delves into the history of neurosurgery, tracing the evolution of the field from ancient times to the present day.

Through his writing, the author conveys a deep sense of empathy and compassion for his patients and their families.

Some of the cases he describes are:

The Musician’s Tumor: Schwartz recounts the case of a professional violinist who had a brain tumor. The surgery was particularly challenging because it was crucial to preserve the patient’s fine motor skills and musical abilities. During the operation, the patient was kept awake and played the violin, allowing Schwartz to ensure that the areas of the brain responsible for these skills were not damaged.
The Young Athlete: Another compelling case involves a young athlete who suffered a severe head injury. Schwartz describes the delicate process of removing a blood clot from the brain and the subsequent rehabilitation that allowed the patient to return to sports. This case highlights the resilience of the human brain and the importance of timely medical intervention.
The Phantom Limb: Schwartz also delves into the phenomenon of phantom limb pain through the story of a patient who experienced severe pain in a limb that had been amputated. The case explores the brain’s complex relationship with the body and how neurosurgery can sometimes alleviate such mysterious conditions.
The Epilepsy Patient: One of the most intriguing cases involves a patient with severe epilepsy. Schwartz performed a surgery to remove the part of the brain causing the seizures. The case is notable for the precision required and the dramatic improvement in the patient’s quality of life post-surgery.

The personal stories of patients provide a humanizing touch to the hard science, making it clear that the brain is more than just an organ—it’s the core of who we are as individuals. These stories give weight to the philosophical questions Schwartz raises: How far can we push the boundaries of human cognition? What are the risks of tampering with the essence of humanity? The discussion of the challenges of making life-and-death decisions and the impact of brain injuries on individuals and their families is unsettling and thought-provoking.

In addition to its medical and personal insights, GRAY MATTERS offers a valuable perspective on the future of neurosurgery. Schwartz discusses emerging technologies, such as brain-computer interfaces and gene therapy, and their potential to revolutionize the treatment of brain disorders. He also addresses the ethical concerns that may arise as these technologies become more advanced.

While the book is primarily focused on the medical aspects of neurosurgery, Schwartz also touches on the personal toll that this demanding profession can take on practitioners. His reflections on the emotional challenges of dealing with life-and-death situations provide a valuable perspective on the human side of medicine.

This is an intellectually stimulating read that merges science and philosophy seamlessly. The book is a compelling blend of memoir and textbook and is a highly recommended read for anyone interested in the brain, medicine, or the human condition. However, those looking for a purely philosophical or speculative work might feel that the book is too grounded in clinical reality.

Regardless, Schwartz’s expertise and passion for his field shine through on every page, making this book a fascinating and informative exploration of the complexities of the human mind and the incredible advancements that have been made in the field of neurosurgery.

Want your own copy? You can pick it up here.

THE LIVING MEDICINE: HOW A LIFESAVING CURE WAS NEARLY LOST by Lina Zeldovich

October 22, 2024 / Kyle Wendy Skultety / 0 Comments

The dramatic, tragic, long-suppressed story of a forgotten and life-saving cure, and the scientists who discovered and are now reviving it
First discovered in 1917, bacteriophages—or “phages”—are living viruses that devour bacteria. Ubiquitous in the environment, they are found in water, soil, inside plants and animals, and in the human body. When phages were first recognized as medicines, their promise seemed limitless. Grown by research scientists and physicians in France, the Soviet Union, and elsewhere to target specific bacteria, they cured cholera, dysentery, bubonic plague, and other deadly infectious diseases. But after Stalin’s brutal purges and the rise of antibiotics, phage therapy declined and nearly was lost to history—until today.
In The Living Medicine, acclaimed science journalist Lina Zeldovich reveals the remarkable history of phages, told through the lives of the French, Soviet, and American scientists who discovered, developed, and are reviving this unique cure for seemingly intractable diseases. Ranging from Paris to Soviet Georgia to Egypt, India, South Africa, remote islands in the Far East, and America, The Living Medicine shows how phages once saved tens of thousands of lives. Today, with our antibiotic shield collapsing, Zeldovich demonstrates how phages are making our food safe and, in cases of dire emergency, rescuing people from the brink of death. They may be humanity’s best defense against the pandemics to come.
Filled with adventure, human ambition, tragedy, technology, irrepressible scientists and the excitement of their innovation, The Living Medicine offers a vision of how our future may be saved by knowledge from the past.

Thanks to NetGalley and the publisher for this review copy!

Lina Zeldovich’s book, The Living Medicine: How a Lifesaving Cure Was Nearly Lost—and Why It Will Rescue Us When Antibiotics Fail, explores the world of bacteriophages, or phages. These are viruses that specifically infect and kill bacteria, offering a potential solution to the growing crisis of antibiotic resistance.

The book delves into the tumultuous history of phages, from their discovery in 1917 to their near obscurity as antibiotics took center stage in the mid-20th century. Zeldovich explores the reasons behind this shift, including the ease of production, the use of antibiotics compared to phages, and the rise of powerful pharmaceutical companies.

However, with the growing problem of antibiotic-resistant bacteria, phages are re-emerging as a potential weapon in our fight against infectious diseases. The book examines the current research and development efforts around phage therapy, highlighting its potential to combat a wide range of infections.

As antibiotic resistance escalates into a global health crisis, Zeldovich’s work becomes both timely and essential, shedding light on an ancient remedy that may hold the key to our future.

Zeldovich’s storytelling is engaging and accessible, skillfully blending rigorous scientific detail with personal narratives and historical context. She delves into the lives of pioneering scientists who first discovered and utilized phages, such as Félix d’Hérelle and George Eliava, and navigates through the complex socio-political landscapes that influenced their work.

She also provides a detailed account of the geopolitical dynamics that influenced medical research, especially during the Cold War era. In the West, antibiotics became the standard treatment for bacterial infections, leading to the neglect of phage therapy. Meanwhile, in places like Georgia, phage research flourished, resulting in a rich repository of knowledge and experience that has now become invaluable as the world faces the looming crisis of antibiotic resistance.

The author’s ability to weave together historical accounts and scientific explanations makes for a compelling and thought-provoking read. She also adds anecdotes and case studies, illustrating the profound impact of phage therapy on individuals who had exhausted all other medical options. These stories not only humanize the science but also serve as powerful testimonials to the efficacy of phages.

Her personal connection to the topic adds a rich layer to the narrative. Zeldovich draws on her family’s experiences in the Soviet Union, where phage therapy was a common and successful practice. This intimate frame of reference enriches the book, providing a unique perspective on how cultural and political factors shape scientific advancements and healthcare practices.

Zeldovich also explores the innovative research and technological advancements that are propelling phages back into the spotlight. She discusses the potential of genetic engineering to enhance phage efficacy and the promise of personalized medicine tailored to individual patients’ infections. The book builds a compelling argument for why phages should be integrated into the mainstream medical arsenal, especially as the pipeline for new antibiotics dries up. The author also emphasizes the global implications of antibiotic resistance and the need for international collaboration in combating bacterial infections. She highlights how phages offer a ray of hope not only for wealthy nations grappling with antibiotic resistance but also for low-resource settings where access to antibiotics is limited.

Strengths:

THE LIVING MEDICINE tackles a critical issue in public health: antibiotic resistance. As antibiotics become less effective, phages offer a promising alternative. The book also provides a historical perspective on phage therapy, explaining its decline and resurgence.

The narrative is enriched with vivid descriptions and compelling characters, from passionate scientists to desperate patients, which keeps the reader invested throughout.

Concerns:

The book focuses heavily on the potential of phages, with less exploration of the current challenges in bringing phage therapy to mainstream medicine. While the book avoids overly technical jargon, there are sections that might be challenging for readers unfamiliar with scientific concepts. At times, the story jumps from one focus to another, making it sometimes hard to follow the narrative.

While THE LIVING MEDICINE is largely an optimistic account of phages’ potential, Zeldovich does not shy away from discussing the challenges. She addresses the regulatory hurdles, the need for rigorous clinical trials, and the skepticism within the medical community. However, some readers may find the book’s enthusiasm for phages occasionally overshadows these critical perspectives.

This book is a well-researched and informative book that sheds light on a promising area of medical research. It offers a compelling look at phages and their potential to revolutionize how we treat infectious diseases. It is important to note that phage therapy is still in its preliminary stages of development, and more research is needed to determine its efficacy and safety for widespread use. The book does seem to be grounded in scientific research, making the potential of phage therapy seem authentic. To me, it seems like it was written with a scientific background in mind. To that end, this book is highly recommended for medical professionals, microbiologists, and anyone interested in the evolving landscape of healthcare. It also serves as a valuable resource for policy makers and educators looking to understand and address the challenges posed by antibiotic resistance. Zeldovich’s work serves as both a wakeup call and a beacon of hope. This book not only informs but also inspires, making a compelling case for the revival of phage therapy in modern medicine.

Want your own copy? You can pick it up here.

AN ARTIST AMONG THE WIND HORSES OF MONGOLIA by Erika Connor

May 14, 2024 / Kyle Wendy Skultety / 0 Comments

An artist visits Hustai National Park in Mongolia and takes part in the reintroduction project of the wild Przewalski horses, or Wind Horses as they are known by Mongolians. A reflection on the story of humans and horses in the wilderness, illustrated with 36 original colour paintings. Searching for her place in the world, she finds company with wild horses and explores the interplay between the herd and the lone wolf.
“I slipped across the grasses, becoming one with the trees and rocks. Sometimes, they passed so close I could have reached out my hand to skim their hides, the ribs, the last of their tattered winter coats.”
“It was natural then that I’d made my way here, having been affected and altered by horses throughout my life.”
An excerpt of this work was published in Travelers’ The Best Travel Writing 2009, under the title, “In a Place of Wind”.

Thanks to Library Thing and Petra Books for this review copy!

Erika Connor’s “An Artist Among the Wind Horses of Mongolia” is more than just a travelogue; it’s a captivating immersion into the Mongolian wilderness and the cultural reverence for the wild Przewalski horse. The “Wind Horses,” as they are called by the locals, are the focus of both Connor’s artistic journey and the reintroduction project she participates in at Hustai National Park.

The Wind Horse is a Buddhist concept depicting the soul. A winged horse with a flaming jewel on its back is seen on Tibetan prayer flags flying in the wind from the highest mountain tops. It is also portrayed on the Mongolian coat of arms. The Mongolians have a word, khiimori. that is difficult to translate, but it is said to represent the Wind Horse and embodies the human soul, a life force.

The book follows Connor’s firsthand experience volunteering with the Wind Horses in Hustai National Park. Connor’s narrative is rich with vivid descriptions, transporting the reader to the vast grasslands and under the boundless Mongolian sky. You’ll feel the wind whipping through your hair, sense the sun warming your skin, and smell the earthy scent of the steppe as you journey alongside her. Readers with a passion for art will find Connor’s experience particularly engaging. She details her artistic process as she attempts to capture the essence of the wild horses and the nomadic culture surrounding them.

I had been here on the edge of unknown for three days now, on the shoreline of fifty thousand hectares of steppeland.

…a raven swooped by on my right, so close I could see the gloss of his blue-black feathers and the glint of his eye. What came back to me again and again was the gaze of animals. In that gaze was the wordless kinship with the original life source. It seemed observer and observed were the same.

The winds yanked the handle of the painted door out of my hands and I stumbled out of my ger, hitting my head on the doorframe. I wondered if there was a Mongolian saying about starting your day like this.

There was always the feeling of odyssey before getting on a horse, a suspension of time and certainty, lifting the feet, leaving the earth.

Through vivid descriptions and evocative storytelling, readers are introduced to a diverse cast of characters—from nomadic herders to skilled artisans—each contributing to the tapestry of Mongolia’s cultural landscape. This adds another layer to the story, creating a well-rounded picture of the region and its people.

One of the book’s most striking aspects is its exploration of the symbiotic relationship between art and nature. As the author delves deeper into the Mongolian wilderness, she finds inspiration in the untamed beauty of the landscape, channeling its energy into their own creative pursuits. Whether painting the sweeping vistas of the Gobi Desert or capturing the spirit of the wild horses that roam the steppe, the author’s passion for her craft shines through on every page.

But Connor’s true strength lies in capturing the essence of the human-horse connection so deeply ingrained in Mongolian culture. She weaves together personal anecdotes with insights into the nomadic way of life, where horses are not just companions, but vital partners in survival.

Moreover, “An Artist Among the Wind Horses of Mongolia” offers profound insights into the enduring spirit of the Mongolian people. Through encounters with local communities and intimate conversations with herders, the author uncovers the resilience and resourcefulness that define Mongolian culture. From the warmth of traditional hospitality to the profound reverence for nature, readers gain a deeper appreciation for the values that unite this ancient civilization.

The book is beautifully complemented by Connor’s original paintings (36 in total), which bring the landscape and the wild horses to life. These illustrations aren’t mere decorations; they serve as an extension of the narrative, offering a visual window into the soul of the Mongolian wilderness.

Thoughts:

While not explicitly mentioned, it seems the book would be best enjoyed by those with an interest in conservation efforts. Connor’s involvement in the Przewalski horse reintroduction project adds a layer of purpose to the narrative. However, the book is heavily weighted towards the artistic side of the project, with detailed descriptions of the landscape and the horses themselves. Readers seeking a more scientific approach to the reintroduction project might want to look elsewhere.

Since the book includes illustrations, it might be more enjoyable in a physical format to fully appreciate the artwork alongside the text.

“An Artist Among the Wind Horses of Mongolia” is a perfect read for anyone who loves a good travelogue, has a passion for horses, or simply appreciates a well-written story about nature and cultural connection. It’s a testament to the power of art to bridge cultures and inspire a deeper appreciation for the natural world.

Want your own copy? You can pick it up here.

TO CURE OR KILL by Michael Young

December 19, 2023 / Kyle Wendy Skultety / 0 Comments

This is a frightening story describing the scientific discovery of a new cancer medication, and the greed and quest for wealth within the pharmaceutical industry. The book delves into the world of scientific development, executive entitlement, and the ruthless efforts to obtain a needed molecular synthesis protocol to advance a new drug. At the end of the novel, the reader will need to ask themselves the underlying question: Is this story really fiction?

Thanks to Reedsy Discovery for this review copy!

In this frightening novel, author Michael Young delves into the dark side of the pharmaceutical industry, where greed and ambition clash with the pursuit of life-saving cures. The story revolves around a groundbreaking discovery of a new cancer-preventing drug and the ruthless individuals who will stop at nothing to exploit it for their own gain. The captivating narrative weaves together scientific intrigue, corporate espionage, and moral quandaries, keeping the reader interested until the very end. The novel’s exploration of the ethical boundaries of scientific research is particularly thought-provoking, raising questions about the balance between profit and human health.

The characters are complex and believable, making you care about their fate. Most of the scientists in this book are created as sympathetic characters (rather than science nerds), and the bad guys are so easy to hate! The author has done a thorough job of creating arrogant, narcissistic criminals, and I was impressed at how he was able to create a plausible story line that delved into the mind of the villains as they planned their heinous actions.

The novel is suspenseful, with plenty of twists and turns to keep you guessing. I also appreciated the accurate medical details: as a physician, Young clearly has a deep understanding of the medical field, which adds to the realism of the story. It is detailed yet easy for the layman to understand. These details may also serve to educate the reader about DNA, , mRNA, how new drugs are created, and medical ethics. There are also extensive descriptions of various poisons and how to use them for nefarious purposes.

One of the author’s strengths is the way he uses adjectives to create a picture. I particularly liked the description of the inside of a character’s home: “Burksdale made a final look around the rather boring, sullen, apartment…”. Another few sentences of note: “With his good looks, self-confidence, and obvious intelligence, Bob could walk into any room and light it up. The women adored him, and the men wanted to be him.”

I also learned some more about company security. We are all subject to phishing and identity theft, and I liked how the tone of chapter 9 was set by chapter 8’s discussing the internet of things and how hackers operate.

This book made me think about medical ethics and corporate greed. The drug companies in the United States are at times both helpful and a hindrance. Lifesaving drugs are created, yet they are ridiculously overpriced, and people may have to choose between food on the table or the medication that makes their quality of life better. It is also very frightening to consider that corporate espionage goes on every day, and we may never find out about it.

Some things I disliked about the book were: simple editing errors regarding spelling (pored over, NOT poured over!) and the author’s excessive use of italics. He used them in many instances where they were not needed. For example: italics are used for all company names (Harris Therapeutics) and websites (Google, Facebook). This became jarring to me, as I normally associate italics being used for emphasis, not to discern a company name or website, etc. Eventually I got italics fatigue and viewed it all like the boy crying wolf.

Another unpleasant idiosyncrasy I noted: the verb tenses were often not compatible with each other within the same sentence. For example, on page 69 the sentence moves from past tense to present: “…Burksdale WAS able to assemble a list….it IS frightening how much personal information IS available online…” And again, from page 73: “Traffic on the expressway CAN BE brutal during rush hour, and getting off late WOULD BE a miserable waste of time”. It was as if the author was writing an aside to the reader to make a point of explaining something. This too, became grating to me, as the English major in me cringed every time I came upon it. It took me away from being absorbed in the story to shuddering and replacing the verb tense in my mind. I have not read any other of Young’s books, so I have no way of knowing if this is a one-off in this particular book, or if that is his true writing style.

One final note: I thought the ending was a bit abrupt. I would have liked to see a little more detail about some of the characters and how their lives were affected.

In Summary: TO CURE OR KILL is a thrilling tale of greed, ambition, and the pursuit of scientific breakthroughs, with a cautionary message about the potential dangers of unchecked ambition. It is also a timely and relevant novel that sheds light on the often-hidden world of pharmaceutical research. The novel explores important themes such as the ethics of scientific research, the greed of corporations, and the power of hope. The plot is a blend of fiction and reality, and the author challenges the reader to question whether such a story could happen.

This book is a must-read for anyone interested in the intersection of medicine, business, and ethics. Fans of medical thrillers and suspenseful fiction will also enjoy this book. I recommend this book to anyone who enjoys reading the works of Robin Cook, Michael Palmer, and Sandeep Jauhar.

Want your own copy? You can pick it up here.

SAY ANARCHA by J.C. Hallman

August 29, 2023 / Kyle Wendy Skultety / 0 Comments

A compelling reckoning with the birth of women’s health that illuminates the sacrifices of a young woman who changed the world only to be forgotten by it―until now.

For more than a century, Dr. J. Marion Sims was hailed as the “father of modern gynecology.” He founded a hospital in New York City and had a profitable career treating gentry and royalty in Europe, becoming one of the world’s first celebrity surgeons. Statues were built in his honor, but he wasn’t the hero he had made himself appear to be.
Sims’s greatest medical claim was the result of several years of experimental surgeries―without anesthesia―on a young, enslaved woman known as Anarcha; his so-called cure for obstetric fistula forever altered the path of women’s health.
One medical text after another hailed Anarcha as the embodiment of the pivotal role that Sims played in the history of surgery. Decades later, a groundswell of women objecting to Sims’s legacy celebrated Anarcha as the “mother of gynecology.” Little was known about the woman herself. The written record would have us believe Anarcha disappeared; she did not.

Through tenacious research, J. C. Hallman has unearthed the first evidence of Anarcha’s life that did not come from Sims’s suspect reports. Hallman reveals that after helping to spark a patient-centered model of care that continues to improve women’s lives today, Anarcha lived on as a midwife, nurse, and “doctor woman.”
SAY ANARCHA excavates history, deconstructing the biographical smoke screen of a surgeon who has falsely been enshrined as a medical pioneer and bringing forth a heroic Black woman to her rightful place at the center of the creation story of modern women’s health care.

Thanks to NetGalley and Henry Holt Company for this review copy!

SAY ANARCHA by JC Hallman is a remarkable work that transports readers to the haunting realities of 19th-century America, where the harrowing echoes of enslaved African American women’s lives reverberate through time. This powerful novel delves deep into the forgotten pages of history, weaving a compelling narrative that is as heart-wrenching as it is enlightening.

The story revolves around Anarcha, one of the countless enslaved women subjected to Dr. Marion Sims’ inhumane medical experiments in his quest to perfect the technique of gynecological surgery. a white doctor who is often credited with the invention of modern gynecology.

Drawing inspiration from historical events, the author masterfully combines fact and fiction, bringing the agonizing experiences of Anarcha and her fellow enslaved women to life with vivid prose. Hallman’s writing effortlessly transports readers to the 19th-century Southern United States, immersing them in a world of suffering and hope. This strength was also a weakness to me, as I felt bogged down by all the history. At one point I decided to start skipping over the incredible details and concentrate on Anarcha and the other major characters. These are my thoughts; others may welcome history as a refresher, or as new knowledge.

The book begins with a brief overview of Sims’s life and work. Sims was a brilliant surgeon, but he was also a deeply flawed man who was willing to exploit the most vulnerable members of society in his quest for medical knowledge. In 1846, Sims began performing experimental surgeries on Anarcha, who had suffered a severe vesicovaginal fistula, a condition that causes urine to leak into the vagina. Sims performed these surgeries without anesthesia, and Anarcha endured unimaginable pain and suffering. She eventually died from complications from all her surgeries.

The book is divided into two parts. The first part tells the story of Anarcha’s life, from her childhood in slavery to her years of suffering at the hands of Sims. The second part tells the story of Sims’ rise to fame as the “Father of Gynecology.” Sims’ innovations were built upon the suffering and exploitation of Anarcha and other enslaved women. Hallman weaves a vivid tapestry of historical accounts, immersing readers in the cruel reality faced by Anarcha and countless others, while shedding light on the often-neglected narratives of African American women in history.

Hallman’s book does not shy away from the horrors of Anarcha’s story. He describes in detail the surgeries that Sims performed on her, and he also explores the psychological and emotional toll that these surgeries took on Anarcha. However, Hallman also does a masterful job of humanizing Anarcha. He shows us that she was a complex and resilient woman who was determined to survive and thrive, even in the face of unspeakable cruelty. Despite the horrific abuse she suffered, Anarcha never gave up hope. She continued to fight for her freedom, and she eventually won her release from slavery.

One of the book’s strengths is the author’s ability to blend history with imagination, breathing life into Anarcha and the other characters surrounding her. Hallman’s meticulous research is evident, as he brings to light the horrors of slavery and the atrocities committed in the name of medical progress.

The novel also explores the perspectives of those around Anarcha, including Dr. Sims himself. This multi-dimensional approach adds depth to the narrative, forcing readers to confront the uncomfortable truths about the moral and ethical dilemmas faced by those complicit in perpetuating the system of slavery. The portrayal of Dr. Sims is particularly nuanced, exploring the complexity of his character as both a pioneering surgeon and a morally flawed individual. For all his knowledge, he was extremely self-centered and didn’t even care about women’s health as he was going through medical school! I feel that he did everything solely to make his name known, not out of compassion.

“Say Anarcha” may not be for the faint of heart due to its graphic descriptions of medical procedures and the harsh realities of slavery. Readers should be prepared for an emotionally intense journey that forces them to confront the uncomfortable truths of history.

Want your own copy? You can pick it up here.

RANDOM ACTS OF MEDICINE by Anupam B. Jena & Christopher Worsham

August 15, 2023 / Kyle Wendy Skultety / 0 Comments

A groundbreaking book at the intersection of health and economics, revealing the hidden side of medicine and how unexpected—but predictable—events can profoundly affect our health. Why do kids born in the summer get diagnosed more often with A.D.H.D.? How are marathons harmful for your health, even when you’re not running? What do surgeons and salesmen have in common? Which annual event made people 30 percent more likely to get COVID-19?
As a University of Chicago–trained economist and Harvard medical school professor and doctor, Anupam Jena is uniquely equipped to answer these questions. And as a critical care doctor at Massachusetts General who researches health care policy, Christopher Worsham confronts their impact on the hospital’s sickest patients. In this singular work of science and medicine, Jena and Worsham show us how medicine really works, and its effect on all of us.

Relying on ingeniously devised natural experiments—random events that unknowingly turn us into experimental subjects—Jena and Worsham do more than offer readers colorful stories. They help us see the way our health is shaped by forces invisible to the untrained eye. Is there ever a good time to have a heart attack? Do you choose the veteran doctor or the rookie?  Do you really need the surgery your doctor recommends? These questions are rife with significance; their impact can be life changing. Addressing them in a style that’s both animated and enlightening, Random Acts of Medicine empowers you to see past the white coat and find out what really makes medicine work—and how it could work better.

Thanks to Doubleday Books for this review copy! Authors Anupam B. Jena and Christopher Worsham have collaborated on a fascinating and eye-opening book at the intersection of health and economics. The book explores the surprising and often counterintuitive ways that medicine works. The authors, both doctors and researchers at Harvard Medical School, use natural experiments—random events that create natural comparisons among people—to reveal the hidden factors that influence our health outcomes.

Jena and Worsham look at medicine from a few different angles, including the role of chance and luck, the power of natural experiments, and the future of healthcare. Jena and Worsham do an excellent job of explaining complex concepts in a way that is easy to understand.

The book is divided into three parts: “The Hidden Side of Medicine,” “The Power of Natural Experiments,” and “The Future of Medicine.” In the first part, Jena and Worsham explore the ways in which chance and luck play a role in our health. They discuss how our birthdate, our zip code, and even our name can all influence our health outcomes.

In the second part of the book, Jena and Worsham introduce the concept of natural experiments. Natural experiments are events that happen outside of a doctor’s control, but which can be used to learn about the effects of different medical treatments or interventions. For example, Jena and Worsham discuss how the introduction of a new drug can be used to study the effects of that drug on a population of patients.

In the third part of the book, Jena and Worsham look at the future of medicine. They discuss how the rise of big data and artificial intelligence is changing the way we understand and treat disease. They also discuss the challenges that we face in making sure that everyone has access to high-quality healthcare.

For example, they show how kids born in the summer are more likely to be diagnosed with ADHD, how marathons can harm your health even if you don’t run, how surgeons and salesmen have similar incentives, and how an annual event made people 30 percent more likely to get COVID-19. The book is full of intriguing stories and insights that challenge our assumptions and make us think differently about medicine and health care.

The book is also written in a clear and engaging style that makes it accessible and enjoyable for anyone interested in learning more about the science and economics of medicine. The authors combine rigorous research with personal anecdotes and humor to illustrate their points and keep the reader hooked. They also offer practical advice on how to make better decisions for ourselves and our loved ones when it comes to our health. One caveat: I felt the book was a bit long. I think it could have been shorter without losing any of the valuable information.

Random Acts of Medicine is an informative read for anyone who wants to understand how medicine really works, and how it could work better. It will make you smarter, healthier, and more informed about one of the most important aspects of our lives. I recommend it to anyone who is interested in learning more about the hidden side of medicine, the power of natural experiments, and the future of healthcare.

Want your own copy? You can pick it up here.

WOMB by Leah Hazard

March 7, 2023 / Kyle Wendy Skultety / 0 Comments

A groundbreaking, triumphant investigation of the uterus—from birth to death, in sickness and in health, throughout history and into our possible future—from midwife and acclaimed writer Leah Hazard

The size of a clenched fist and the shape of a light bulb—with no less power and potential. Every person on Earth began inside a uterus, but how much do we really understand about the womb? Bringing together medical history, scientific discoveries, and journalistic exploration, Leah Hazard embarks on a journey in search of answers about the body’s most miraculous and contentious organ. We meet the people who have shaped our relationship with the uterus: doctors and doulas, yoni steamers and fibroid-tea hawkers, legislators who would regulate the organ’s very existence, and boundary-breaking researchers on the frontiers of the field. With a midwife’s warmth and humor, Hazard tackles pressing questions: Is the womb connected to the brain? Can cervical crypts store sperm? Do hysterectomies affect sexual pleasure? How can smart tampons help health care? Why does endometriosis take so long to be diagnosed? Will external gestation be possible in our lifetime? A clear-eyed examination of the cultural prejudices and assumptions that have made the uterus so poorly understood for centuries, Womb takes a fresh look at an organ that brings us pain and pleasure—a small part of our bodies that has a larger impact than we ever thought possible.

Thanks to NetGalley and Ecco for this review copy!

Every woman has one, but do they understand what the womb really does? Once you read this informative book you will be so happy the author wrote it.

When I saw that a midwife authored this book, I knew that it would be relevant, detailed, and female friendly. The womb is regulated by the government, dismissed by some physicians, and disparaged by men. It is also a misunderstood organ, considered to be simply the place where the fetus lives. That could not be farther from the truth! The uterus has far -reaching effects upon a woman, more than just the cause of mood swings each month during menstruation.

Each chapter discusses a different subject, such as endometriosis, hysterectomies, transplants (yes, you can put a uterus into a woman just like a heart transplant) hormones, and the various stages of the womb from first menses to menopause. The final chapters are reminiscent of BRAVE NEW WORLD, as the author discusses the possibility of an external uterus (called a biobag) and ways that a woman could be pregnant even without a womb.

There are stories in each chapter that make you realize just how much this organ is ignored and how men have used and abused it, from Josef Mengele’s experiments to the eugenics movement in the United States. Some of the details are cringeworthy, such as the woman who tried to remove her own uterus, or the story of the doctor at the Irwin County Detention Center whom they called the “uterus collector”.

Since Roe v. Wade has been overturned, women’s reproductive rights have been at the forefront of a great deal of news cycles. It seems unreal how the government, especially male politicians, have the final say on whether a woman can end her pregnancy or not. Regardless of your convictions (pro-choice or pro-life), it is unfathomable that a woman has no control over her own organs.

This book should be required reading for anyone that has a uterus. There are so many amazing facts and thought-provoking ideas – it’s almost guaranteed that you will learn something as you read WOMB. The author’s writing style is easy to understand, as she explains the science and history of this wonderful organ in a way that will make you want to keep reading.

Want your own copy? You can pick it up here.

The Truth About Animals by Lucy Cooke

January 28, 2020 / Kyle Wendy Skultety / 0 Comments

Mary Roach meets Bill Bryson in this “surefire summer winner” (Janet Maslin, New York Times), an uproarious tour of the basest instincts and biggest mysteries of the animal world

Humans have gone to the Moon and discovered the Higgs boson, but when it comes to understanding animals, we’ve still got a long way to go. Whether we’re seeing a viral video of romping baby pandas or a picture of penguins “holding hands,” it’s hard for us not to project our own values–innocence, fidelity, temperance, hard work–onto animals. So, you’ve probably never considered if moose get drunk, penguins cheat on their mates, or worker ants lay about. They do–and that’s just for starters. In The Truth About Animals, Lucy Cooke takes us on a worldwide journey to meet everyone from a Colombian hippo castrator to a Chinese panda porn peddler, all to lay bare the secret–and often hilarious–habits of the animal kingdom. Charming and at times downright weird, this modern bestiary is perfect for anyone who has ever suspected that virtue might be unnatural.

Thanks to NetGalley for this review copy!

This book reads like it was written by the love child of Charles Darwin and Mary Roach. There is humor, pathos, and animal facts aplenty. The author’s writing style is easy to read and captured my attention immediately. The love Cooke has for these beasties is obvious from the start. Hopefully, given the facts, others will learn to appreciate these maligned characters that occupy the animal world.

Each chapter is devoted (lovingly) to a misunderstood animal, where we find myths debunked through modern science. The reader will learn about sloths, bats, and hyenas, to name a few. The author will discuss how the animals were experimented on/studied over hundreds of years (Who knew that Aristotle was a proponent of spontaneous creation?) then we get to modern times, where myths are debunked and the many reasons to love these animals are revealed.

Some of the experiments detailed can be a bit gory, such as when, in the 18^th century, the Catholic priest Lazzaro Spallanzani practiced blinding bats to find out how they managed to find their way around in darkness. (He also coated them in varnish for another experiment, but I digress). Other tales are edifying and satisfying, such as:

It may sound suspiciously like bogus medieval folk medicine, but from the 1940s through the 1960s the world’s first reliable pregnancy test was a small, bug-eyed frog. When injected with a pregnant woman’s urine, the amphibian didn’t turn blue or display stripes, but it did squirt out eggs 8-12 hours later to confirm a positive result.

Cooke’s book is full of factoids like that one. How can you not love this book? You will learn, you will laugh, and you will be full of obscure information. That sounds like a winner to me.

Yes, you want your own copy and can pick it up here.

The Body by Bill Bryson

October 15, 2019 / Kyle Wendy Skultety / 0 Comments

In the bestselling, prize-winning A Short History of Nearly Everything Bill Bryson achieved the seemingly impossible by making the science of our world both understandable and entertaining to millions of people around the globe.

Now he turns his attention inwards to explore the human body, how it functions and its remarkable ability to heal itself. Full of extraordinary facts and astonishing stories The Body: A Guide for Occupants is a brilliant, often very funny attempt to understand the miracle of our physical and neurological make up.

A wonderful successor to A Short History of Nearly Everything, this book will have you marvelling at the form you occupy, and celebrating the genius of your existence, time and time again.

Thanks to NetGalley for this ARC!

Did you ever wonder how many times a day you blink? Or who invented the calorie and why we are so obsessed with counting them? These answers and a multitude of others can be found in THE BODY, a wonderfully wry book of facts and stories about, well, the body we occupy. Each chapter is devoted to one of the body’s systems (the gut, the nervous system, as well as sleep and the function of glands, etc) so as to build upon the last chapter’s information. Here’s an interesting factoid from the food chapter: fruits have been genetically manipulated to be sweeter than they were hundreds of years ago. The author purports that apples in Shakespeare’s day were no sweeter than today’s carrots.

I’m trying to decide whether Bryson’s droll wit or the abundance of information about our body is the best part of the book. You will end up learning things without even trying – there isn’t any deep scientific talk so you don’t need a degree in biology to easily read this book.

There isn’t a plot so much as a description of the body part, its function, and then facts and history about it. For example, in the chapter entitled “Gut” we learn how our digestive system works, then we learn about E. coli and other dangerous microbes, there is a bit about food safety, and then it’s 1822 and we are reading about an unfortunate accident that left a hole in a fur trapper’s stomach. This fur trapper eventually became something of a living experiment due to the injury (Google “Beaumont and St Martin” for more details if you wish).

This was an illuminating and droll read – one of the better books I have read this summer. Run, don’t walk to get your copy! You will be thoroughly enlightened and entertained, and even a bit grossed out – in a good way.

You can pick up your copy here.

Influenza by Jeremy Brown

January 22, 2019 / Kyle Wendy Skultety / 0 Comments

On the 100th anniversary of the devastating pandemic of 1918, Jeremy Brown, a veteran ER doctor, explores the troubling, terrifying, and complex history of the flu virus, from the origins of the Great Flu that killed millions, to vexing questions such as: are we prepared for the next epidemic, should you get a flu shot, and how close are we to finding a cure?

While influenza is now often thought of as a common and mild disease, it still kills over 30,000 people in the US each year. Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu’s deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what’s to come.
Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government’s role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts.
Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people—and warns us that it may be many more years before we are able to conquer it for good.

Thanks to NetGalley for the ARC!

Yes, this is another book on the influenza pandemic of 1918 – my goal is to read them all. Seriously, it is always good to compare one with the other and possibly learn new information. One new angle with this book is that the author discusses the Tamiflu controversy in detail (I wasn’t aware of the issues behind this drug, and the backstory makes the juxtaposition with the pandemic particularly chilling). Another angle is that this book is not restricted to the 1918 outbreak; there is a discussion of the virus in general, what type of research has been done, and puts forth the probability of when/how another outbreak could be possible.

One of my favorite portions of the book was the story behind the exhumed victims and how the virus was recovered from their bodies. The author’s respect for their sacrifice shines clearly through in this section, which is detailed but not gory. The gore factor is minimal, compared to other books on influenza or diseases in particular.

The fact that the author is a medical doctor means that he’s done his research and can strike the balance between med-speak and conveying his ideas to the general public. The book is very easy to read and eminently understandable. I read this over the course of a few days and it kept me interested throughout. It is always refreshing when an author can take a subject and provide a fresh, relevant look at it.

You can pick up your own copy here.